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Profiling the Interaction Mechanism of Quinoline/Quinazoline Derivatives as MCHR1 Antagonists: An in Silico Method

Melanin concentrating hormone receptor 1 (MCHR1), a crucial regulator of energy homeostasis involved in the control of feeding and energy metabolism, is a promising target for treatment of obesity. In the present work, the up-to-date largest set of 181 quinoline/quinazoline derivatives as MCHR1 anta...

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Detalles Bibliográficos
Autores principales: Wu, Mingwei, Li, Yan, Fu, Xinmei, Wang, Jinghui, Zhang, Shuwei, Yang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200842/
https://www.ncbi.nlm.nih.gov/pubmed/25257526
http://dx.doi.org/10.3390/ijms150915475