Synthesis, Anticonvulsant, Sedative and Anxiolytic Activities of Novel Annulated Pyrrolo[1,4]benzodiazepines

Four new pentacyclic benzodiazepine derivatives (PBDTs 13–16) were synthesized by conventional thermal heating and microwave-assisted intramolecular cyclocondensation. Their anticonvulsant, sedative and anxiolytic activities were evaluated by drug-induced convulsion models, a pentobarbital-induced h...

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Detalles Bibliográficos
Autores principales: Sorra, Kumaraswamy, Chen, Chien-Shu, Chang, Chi-Fen, Pusuluri, Srinivas, Mukkanti, Khagga, Wu, Chi-Rei, Chuang, Ta-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200843/
https://www.ncbi.nlm.nih.gov/pubmed/25238414
http://dx.doi.org/10.3390/ijms150916500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200843/
https://www.ncbi.nlm.nih.gov/pubmed/25238414
http://dx.doi.org/10.3390/ijms150916500

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