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Synthesis, Anticonvulsant, Sedative and Anxiolytic Activities of Novel Annulated Pyrrolo[1,4]benzodiazepines

Four new pentacyclic benzodiazepine derivatives (PBDTs 13–16) were synthesized by conventional thermal heating and microwave-assisted intramolecular cyclocondensation. Their anticonvulsant, sedative and anxiolytic activities were evaluated by drug-induced convulsion models, a pentobarbital-induced h...

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Detalles Bibliográficos
Autores principales:	Sorra, Kumaraswamy, Chen, Chien-Shu, Chang, Chi-Fen, Pusuluri, Srinivas, Mukkanti, Khagga, Wu, Chi-Rei, Chuang, Ta-Hsien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200843/ https://www.ncbi.nlm.nih.gov/pubmed/25238414 http://dx.doi.org/10.3390/ijms150916500

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