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Novel Sustained-Release of Propafenone through Pellets: Preparation and in Vitro/in Vivo Evaluation
In this study, an extrusion-spheronization method was applied successfully to fabricate propafenone hydrochloride (PPF) sustained-release pellets. Using scanning electron microscopy, it was shown that the PPF pellets had a mean size of approximately 950 µm with a spherical shape. The in vitro releas...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200845/ https://www.ncbi.nlm.nih.gov/pubmed/25184949 http://dx.doi.org/10.3390/ijms150915503 |