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Prediction of Multi-Target Networks of Neuroprotective Compounds with Entropy Indices and Synthesis, Assay, and Theoretical Study of New Asymmetric 1,2-Rasagiline Carbamates

In a multi-target complex network, the links (L(ij)) represent the interactions between the drug (d(i)) and the target (t(j)), characterized by different experimental measures (K(i), K(m), IC(50), etc.) obtained in pharmacological assays under diverse boundary conditions (c(j)). In this work, we han...

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Detalles Bibliográficos
Autores principales: Romero Durán, Francisco J., Alonso, Nerea, Caamaño, Olga, García-Mera, Xerardo, Yañez, Matilde, Prado-Prado, Francisco J., González-Díaz, Humberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200850/
https://www.ncbi.nlm.nih.gov/pubmed/25255029
http://dx.doi.org/10.3390/ijms150917035