Targeted Suppression of Chaperone-Mediated Autophagy by miR-320a Promotes α-Synuclein Aggregation

Chaperone-mediated autophagy (CMA) is involved in wild-type α-synuclein degradation in Parkinson’s disease (PD), and LAMP2A and Hsc 70 have recently been indicated to be deregulated by microRNAs. To recognize the regularory role of miR-320a in CMA and the possible role in α-synuclein degradation, in...

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Detalles Bibliográficos
Autores principales: Li, Guobin, Yang, Haiying, Zhu, Dezhang, Huang, Hui, Liu, Guoyuan, Lun, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200851/
https://www.ncbi.nlm.nih.gov/pubmed/25207598
http://dx.doi.org/10.3390/ijms150915845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200851/
https://www.ncbi.nlm.nih.gov/pubmed/25207598
http://dx.doi.org/10.3390/ijms150915845

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