Comparison of the mammalian insulin signalling pathway to invertebrates in the context of FOXO-mediated ageing

Motivation: A large number of experimental studies on ageing focus on the effects of genetic perturbations of the insulin/insulin-like growth factor signalling pathway (IIS) on lifespan. Short-lived invertebrate laboratory model organisms are extensively used to quickly identify ageing-related genes...

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Detalles Bibliográficos
Autores principales: Papatheodorou, Irene, Petrovs, Rudolfs, Thornton, Janet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Discovery Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201157/
https://www.ncbi.nlm.nih.gov/pubmed/25064569
http://dx.doi.org/10.1093/bioinformatics/btu493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201157/
https://www.ncbi.nlm.nih.gov/pubmed/25064569
http://dx.doi.org/10.1093/bioinformatics/btu493

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