Cargando…

Comparison of the mammalian insulin signalling pathway to invertebrates in the context of FOXO-mediated ageing

Motivation: A large number of experimental studies on ageing focus on the effects of genetic perturbations of the insulin/insulin-like growth factor signalling pathway (IIS) on lifespan. Short-lived invertebrate laboratory model organisms are extensively used to quickly identify ageing-related genes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Papatheodorou, Irene, Petrovs, Rudolfs, Thornton, Janet M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Discovery Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201157/ https://www.ncbi.nlm.nih.gov/pubmed/25064569 http://dx.doi.org/10.1093/bioinformatics/btu493

Ejemplares similares

The Role of DNA Methylation in Genome Defense in Cnidaria and Other Invertebrates
por: Ying, Hua, et al.
Publicado: (2022)

GC3-biased gene domains in mammalian genomes
por: Shen, Wenlong, et al.
Publicado: (2015)

Genomic Evidence for Speciation with Gene Flow in Broadcast Spawning Marine Invertebrates
por: Hirase, Shotaro, et al.
Publicado: (2021)

Evolutionary Transition of Promoter and Gene Body DNA Methylation across Invertebrate–Vertebrate Boundary
por: Keller, Thomas E., et al.
Publicado: (2016)

Coemergence of the Amphipathic Helix on Ameloblastin With Mammalian Prismatic Enamel
por: Su, Jingtan, et al.
Publicado: (2022)

Genome-wide histone acetylation data improve prediction of mammalian transcription factor binding sites
por: Ramsey, Stephen A., et al.
Publicado: (2010)

Transitioning between entry and exit from mammalian torpor: The involvement of signal transduction pathways
por: Tessier, Shannon N, et al.
Publicado: (2014)

An Ancient Clade of Penelope-Like Retroelements with Permuted Domains Is Present in the Green Lineage and Protists, and Dominates Many Invertebrate Genomes
por: Craig, Rory J, et al.
Publicado: (2021)

Novel Classes and Evolutionary Turnover of Histone H2B Variants in the Mammalian Germline
por: Raman, Pravrutha, et al.
Publicado: (2022)

Lipidome Evolution in Mammalian Tissues
por: Khrameeva, Ekaterina, et al.
Publicado: (2018)

Intron Length Coevolution across Mammalian Genomes
por: Keane, Peter A., et al.
Publicado: (2016)

Evolution of the Mutation Spectrum Across a Mammalian Phylogeny
por: Beichman, Annabel C, et al.
Publicado: (2023)

Transcriptional feedback in the insulin signalling pathway modulates ageing in both Caenorhabditis elegans and Drosophila melanogaster
por: Ivanov, Dobril K., et al.
Publicado: (2013)

The Genetic Origin of Daunians and the Pan-Mediterranean Southern Italian Iron Age Context
por: Aneli, Serena, et al.
Publicado: (2022)

Diversified Mammalian Visual Adaptations to Bright- or Dim-Light Environments
por: Gai, Yulin, et al.
Publicado: (2023)

Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling
por: Alic, Nazif, et al.
Publicado: (2011)

Loss and Gain of Human Acidic Mammalian Chitinase Activity by Nonsynonymous SNPs
por: Okawa, Kazuaki, et al.
Publicado: (2016)

The Birth and Death of Olfactory Receptor Gene Families in Mammalian Niche Adaptation
por: Hughes, Graham M, et al.
Publicado: (2018)

Dental Calculus as a Tool to Study the Evolution of the Mammalian Oral Microbiome
por: Brealey, Jaelle C, et al.
Publicado: (2020)

Dynamic Evolution of Retroviral Envelope Genes in Egg-Laying Mammalian Genomes
por: Kitao, Koichi, et al.
Publicado: (2023)

Phenotypic categorization of genetic skin diseases reveals new relations between phenotypes, genes and pathways
por: Sadreyev, Ruslan I., et al.
Publicado: (2009)

Computationally predicted gene regulatory networks in molluscan biomineralization identify extracellular matrix production and ion transportation pathways
por: Sleight, Victoria A, et al.
Publicado: (2020)

Human MicroRNAs Originated from Two Periods at Accelerated Rates in Mammalian Evolution
por: Iwama, Hisakazu, et al.
Publicado: (2013)

Natural Selection on the Phase-Separation Properties of FUS during 160 My of Mammalian Evolution
por: Dasmeh, Pouria, et al.
Publicado: (2020)

Experimental Resurrection of Ancestral Mammalian CPEB3 Ribozymes Reveals Deep Functional Conservation
por: Bendixsen, Devin P., et al.
Publicado: (2021)

Evolution of an X-Linked miRNA Family Predominantly Expressed in Mammalian Male Germ Cells
por: Zhang, Fengjuan, et al.
Publicado: (2019)

Low Complexity Regions in Mammalian Proteins are Associated with Low Protein Abundance and High Transcript Abundance
por: Dickson, Zachery W., et al.
Publicado: (2022)

Accelerated Evolution Analysis Uncovers PKNOX2 as a Key Transcription Factor in the Mammalian Cochlea
por: Trigila, Anabella P, et al.
Publicado: (2023)

Complex Evolutionary History of the Mammalian Histone H1.1–H1.5 Gene Family
por: Ponte, Inma, et al.
Publicado: (2017)

Stability-Mediated Epistasis Restricts Accessible Mutational Pathways in the Functional Evolution of Avian Hemoglobin
por: Kumar, Amit, et al.
Publicado: (2017)

Signals of Variation in Human Mutation Rate at Multiple Levels of Sequence Context
por: Aikens, Rachael C, et al.
Publicado: (2019)

Functional insight into Maelstrom in the germline piRNA pathway: a unique domain homologous to the DnaQ-H 3'–5' exonuclease, its lineage-specific expansion/loss and evolutionarily active site switch
por: Zhang, Dapeng, et al.
Publicado: (2008)

Insight into temperature-dependent microRNA function in mammalian hibernators: Perspectives on cold-influenced microRNA/target interaction
por: Biggar, Kyle K, et al.
Publicado: (2014)

Positive Selection during the Evolution of the Blood Coagulation Factors in the Context of Their Disease-Causing Mutations
por: Rallapalli, Pavithra M., et al.
Publicado: (2014)

Tracing Eastern Wolf Origins From Whole-Genome Data in Context of Extensive Hybridization
por: Vilaça, Sibelle T, et al.
Publicado: (2023)

DAF-16/FoxO Directly Regulates an Atypical AMP-Activated Protein Kinase Gamma Isoform to Mediate the Effects of Insulin/IGF-1 Signaling on Aging in Caenorhabditis elegans
por: Tullet, Jennifer M. A., et al.
Publicado: (2014)

Venom Insulins of Cone Snails Diversify Rapidly and Track Prey Taxa
por: Safavi-Hemami, Helena, et al.
Publicado: (2016)

Waxy Phenotype Evolution in the Allotetraploid Cereal Broomcorn Millet: Mutations at the GBSSI Locus in Their Functional and Phylogenetic Context
por: Hunt, Harriet V., et al.
Publicado: (2013)

The Diversity of Class II Transposable Elements in Mammalian Genomes Has Arisen from Ancestral Phylogenetic Splits during Ancient Waves of Proliferation through the Genome
por: Hellen, Elizabeth H.B., et al.
Publicado: (2013)

Tight DNA-protein complexes isolated from barley seedlings are rich in potential guanine quadruplex sequences
por: Sjakste, Tatjana, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_pck4k8iasvgbt0j6q7nnhoj1f2