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Comparison of the Effects of Matrix Metalloproteinase Inhibitors on TNF-α Release from Activated Microglia and TNF-α Converting Enzyme Activity

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that regulate cell-matrix composition and are also involved in processing various bioactive molecules such as cell-surface receptors, chemokines, and cytokines. Our group recently reported that MMP-3, -8, and -9 are upregulated durin...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Jung, Moon, Pyong-Gon, Baek, Moon-Chang, Kim, Hee-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201218/
https://www.ncbi.nlm.nih.gov/pubmed/25414771
http://dx.doi.org/10.4062/biomolther.2014.099