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TI-I-174, a Synthetic Chalcone Derivative, Suppresses Nitric Oxide Production in Murine Macrophages via Heme Oxygenase-1 Induction and Inhibition of AP-1

Chalcones (1,3-diaryl-2-propen-1-ones), a flavonoid subfamily, are widely known for their anti-inflammatory properties. Propenone moiety in chalcones is known to play an important role in generating biological responses by chalcones. In the present study, we synthesized chalcone derivatives structur...

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Detalles Bibliográficos
Autores principales: Kim, Mi Jin, Kadayat, Taraman, Kim, Da Eun, Lee, Eung-Seok, Park, Pil-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201222/
https://www.ncbi.nlm.nih.gov/pubmed/25414768
http://dx.doi.org/10.4062/biomolther.2014.062