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HD047703, a New Promising Anti-Diabetic Drug Candidate: In Vivo Preclinical Studies

G-protein coupled receptor 119 (GPR119) has emerged as a novel target for the treatment of type 2 diabetes mellitus. GPR119 is involved in glucose-stimulated insulin secretion (GSIS) from the pancreatic β-cells and intestinal cells. In this study, we identified a novel small-molecule GPR119 agonist,...

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Detalles Bibliográficos
Autores principales: Kim, SoRa, Kim, Dae Hoon, Kim, Young-Seok, Ha, Tae-Young, Yang, Jin, Park, Soo Hyun, Jeong, Kwang Won, Rhee, Jae-Keol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201229/
https://www.ncbi.nlm.nih.gov/pubmed/25414769
http://dx.doi.org/10.4062/biomolther.2014.035