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Short intronic repeat sequences facilitate circular RNA production

Recent deep sequencing studies have revealed thousands of circular noncoding RNAs generated from protein-coding genes. These RNAs are produced when the precursor messenger RNA (pre-mRNA) splicing machinery “backsplices” and covalently joins, for example, the two ends of a single exon. However, the m...

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Detalles Bibliográficos
Autores principales: Liang, Dongming, Wilusz, Jeremy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201285/
https://www.ncbi.nlm.nih.gov/pubmed/25281217
http://dx.doi.org/10.1101/gad.251926.114