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Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence

In mammalian DNA, cytosine occurs in several chemical forms, including unmodified cytosine (C), 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). 5mC is a major epigenetic signal that acts to regulate gene expression. 5hmC, 5fC, and 5caC a...

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Detalles Bibliográficos
Autores principales: Hashimoto, Hideharu, Olanrewaju, Yusuf Olatunde, Zheng, Yu, Wilson, Geoffrey G., Zhang, Xing, Cheng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201290/
https://www.ncbi.nlm.nih.gov/pubmed/25258363
http://dx.doi.org/10.1101/gad.250746.114