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Synthesis of Unnatural Amino Acids Functionalized with Sterically Shielded Pyrroline Nitroxides

[Image: see text] A series of unnatural amino acids functionalized with sterically shielded pyrroline nitroxides were synthesized. Their reduction by ascorbate/glutathione indicates that l-cysteine functionalized with gem-diethylpyrroline nitroxide is reduced at the slowest rate and is comparable to...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Paletta, Joseph T., Berg, Kathleen, Reinhart, Erin, Rajca, Suchada, Rajca, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201325/
https://www.ncbi.nlm.nih.gov/pubmed/25324010
http://dx.doi.org/10.1021/ol502449r