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Resurfaced Shape Complementary Proteins That Selectively Bind the Oncoprotein Gankyrin

[Image: see text] Increased cellular levels of protein–protein interactions involving the ankyrin repeat oncoprotein gankyrin are directly linked to aberrant cellular events and numerous cancers. Inhibition of these protein–protein interactions is thus an attractive therapeutic strategy. However, th...

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Detalles Bibliográficos
Autores principales: Chapman, Alex M., McNaughton, Brian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201333/
https://www.ncbi.nlm.nih.gov/pubmed/25137482
http://dx.doi.org/10.1021/cb5003834