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Simultaneous Detection of Distinct Ubiquitin Chain Topologies by (19)F NMR

[Image: see text] The dynamic interplay between ubiquitin (Ub) chain construction and destruction is critical for the regulation of many cellular pathways. To understand these processes, it would be ideal to simultaneously detect different Ub chains as they are created and destroyed in the cell. Thi...

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Detalles Bibliográficos
Autores principales: Shekhawat, Sujan S., Pham, Grace H., Prabakaran, Jyothiprashanth, Strieter, Eric R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201340/
https://www.ncbi.nlm.nih.gov/pubmed/25119846
http://dx.doi.org/10.1021/cb500589c