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Synthesis of a Library of Propargylated and PEGylated α-Hydroxy Acids Toward “Clickable” Polylactides via Hydrolysis of Cyanohydrin Derivatives

[Image: see text] A new simple and practical protocol for scalable synthesis of a novel library of propargylated and PEGylated α-hydroxy acids toward the preparation of “clickable” polylactides was described. The overall synthesis starting from readily available propargyl alcohol, bromoacetaldehyde...

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Detalles Bibliográficos
Autores principales: Zhang, Quanxuan, Ren, Hong, Baker, Gregory L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201358/
https://www.ncbi.nlm.nih.gov/pubmed/25255205
http://dx.doi.org/10.1021/jo5016135