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Upregulation of GPR109A in Parkinson’s Disease

BACKGROUND: Anecdotal animal and human studies have implicated the symptomatic and neuroprotective roles of niacin in Parkinson’s disease (PD). Niacin has a high affinity for GPR109A, an anti-inflammatory receptor. Niacin is also thought to be involved in the regulation of circadian rhythm. Here we...

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Detalles Bibliográficos
Autores principales: Wakade, Chandramohan, Chong, Raymond, Bradley, Eric, Thomas, Bobby, Morgan, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201464/
https://www.ncbi.nlm.nih.gov/pubmed/25329911
http://dx.doi.org/10.1371/journal.pone.0109818