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Effects of miR-33a-5P on ABCA1/G1-Mediated Cholesterol Efflux under Inflammatory Stress in THP-1 Macrophages

The present study is to investigate whether inflammatory cytokines inhibit ABCA1/ABCG1-mediated cholesterol efflux by regulating miR-33a-5P in THP-1 macrophages. We used interleukin-6 and tumor necrosis factor-alpha in the presence or absence of native low density lipoprotein (LDL) to stimulate THP-...

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Detalles Bibliográficos
Autores principales: Mao, Min, Lei, Han, Liu, Qing, Chen, Yaxi, Zhao, Lei, Li, Qing, Luo, Suxin, Zuo, Zhong, He, Quan, Huang, Wei, Zhang, Nan, Zhou, Chao, Ruan, Xiong Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201478/
https://www.ncbi.nlm.nih.gov/pubmed/25329888
http://dx.doi.org/10.1371/journal.pone.0109722