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Evolution of C, D and S-Type Cystatins in Mammals: An Extensive Gene Duplication in Primates
Cystatins are a family of inhibitors of cysteine peptidases that comprises the salivary cystatins (D and S-type cystatins) and cystatin C. These cystatins are encoded by a multigene family (CST3, CST5, CST4, CST1 and CST2) organized in tandem in the human genome. Their presence and functional import...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201479/ https://www.ncbi.nlm.nih.gov/pubmed/25329717 http://dx.doi.org/10.1371/journal.pone.0109050 |