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Evolution of C, D and S-Type Cystatins in Mammals: An Extensive Gene Duplication in Primates

Cystatins are a family of inhibitors of cysteine peptidases that comprises the salivary cystatins (D and S-type cystatins) and cystatin C. These cystatins are encoded by a multigene family (CST3, CST5, CST4, CST1 and CST2) organized in tandem in the human genome. Their presence and functional import...

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Detalles Bibliográficos
Autores principales: de Sousa-Pereira, Patrícia, Abrantes, Joana, Pinheiro, Ana, Colaço, Bruno, Vitorino, Rui, Esteves, Pedro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201479/
https://www.ncbi.nlm.nih.gov/pubmed/25329717
http://dx.doi.org/10.1371/journal.pone.0109050