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Generation and Characterisation of Mice Deficient in the Multi-GTPase Domain Containing Protein, GIMAP8
BACKGROUND: GTPases of the immunity-associated protein family (GIMAPs) are predominantly expressed in mature lymphocytes. Studies of rodents deficient in GIMAP1, GIMAP4, or GIMAP5 have demonstrated that these GTPases regulate lymphocyte survival. In contrast to the other family members, GIMAP8 conta...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201521/ https://www.ncbi.nlm.nih.gov/pubmed/25329815 http://dx.doi.org/10.1371/journal.pone.0110294 |