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Reduced evolutionary rates in HIV-1 reveal extensive latency periods among replicating lineages

BACKGROUND: HIV-1 can persist for the duration of a patient’s life due in part to its ability to hide from the immune system, and from antiretroviral drugs, in long-lived latent reservoirs. Latent forms of HIV-1 may also be disproportionally involved in transmission. Thus, it is important to detect...

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Detalles Bibliográficos
Autores principales: Immonen, Taina T, Leitner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201670/
https://www.ncbi.nlm.nih.gov/pubmed/25318357
http://dx.doi.org/10.1186/s12977-014-0081-0