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CXCL13 predicts disease activity in early rheumatoid arthritis and could be an indicator of the therapeutic ‘window of opportunity’

INTRODUCTION: A key phenomenon in rheumatoid arthritis is the formation of lymphoid follicles in the inflamed synovial membrane. C-X-C motif chemokine 13 (CXCL13) is central in this process as it attracts C-X-C chemokine receptor type 5 (CXCR5)-expressing B cells and T follicular helper cells to the...

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Detalles Bibliográficos
Autores principales: Greisen, Stinne Ravn, Schelde, Karen Kræmmer, Rasmussen, Tue Kruse, Kragstrup, Tue Wenzel, Stengaard-Pedersen, Kristian, Hetland, Merete Lund, Hørslev-Petersen, Kim, Junker, Peter, Østergaard, Mikkel, Deleuran, Bent, Hvid, Malene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201737/
https://www.ncbi.nlm.nih.gov/pubmed/25249397
http://dx.doi.org/10.1186/s13075-014-0434-z