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Modulation of the stability and activities of HIV-1 Tat by its ubiquitination and carboxyl-terminal region
BACKGROUND: The transactivator of transcription (Tat) protein of human immunodeficiency virus type 1 (HIV-1) is known to undergo ubiquitination. However, the roles of ubiquitination in regulating Tat stability and activities are unclear. In addition, although the 72- and 86-residue forms are commonl...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201738/ https://www.ncbi.nlm.nih.gov/pubmed/25328666 http://dx.doi.org/10.1186/2045-3701-4-61 |