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Modulation of the stability and activities of HIV-1 Tat by its ubiquitination and carboxyl-terminal region

BACKGROUND: The transactivator of transcription (Tat) protein of human immunodeficiency virus type 1 (HIV-1) is known to undergo ubiquitination. However, the roles of ubiquitination in regulating Tat stability and activities are unclear. In addition, although the 72- and 86-residue forms are commonl...

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Detalles Bibliográficos
Autores principales: Zhang, Linlin, Qin, Juan, Li, Yuanyuan, Wang, Jian, He, Qianqian, Zhou, Jun, Liu, Min, Li, Dengwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201738/
https://www.ncbi.nlm.nih.gov/pubmed/25328666
http://dx.doi.org/10.1186/2045-3701-4-61

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