Power analysis and sample size estimation for RNA-Seq differential expression

It is crucial for researchers to optimize RNA-seq experimental designs for differential expression detection. Currently, the field lacks general methods to estimate power and sample size for RNA-Seq in complex experimental designs, under the assumption of the negative binomial distribution. We simul...

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Detalles Bibliográficos
Autores principales: Ching, Travers, Huang, Sijia, Garmire, Lana X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201821/
https://www.ncbi.nlm.nih.gov/pubmed/25246651
http://dx.doi.org/10.1261/rna.046011.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201821/
https://www.ncbi.nlm.nih.gov/pubmed/25246651
http://dx.doi.org/10.1261/rna.046011.114

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