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Ligand binding by the tandem glycine riboswitch depends on aptamer dimerization but not double ligand occupancy
The glycine riboswitch predominantly exists as a tandem structure, with two adjacent, homologous ligand-binding domains (aptamers), followed by a single expression platform. The recent identification of a leader helix, the inclusion of which eliminates cooperativity between the aptamers, has reopene...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201829/ https://www.ncbi.nlm.nih.gov/pubmed/25246650 http://dx.doi.org/10.1261/rna.047266.114 |