Metformin attenuates blood-brain barrier disruption in mice following middle cerebral artery occlusion

BACKGROUND: Metformin, a widely used hypoglycemic drug, reduces stroke incidence and alleviates chronic inflammation in clinical trials. However, the effect of metformin in ischemic stroke is unclear. Here, we investigated the effect of metformin on ischemic stroke in mice and further explored the p...

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Detalles Bibliográficos
Autores principales: Liu, Yanqun, Tang, Guanghui, Li, Yaning, Wang, Yang, Chen, Xiaoyan, Gu, Xiang, Zhang, Zhijun, Wang, Yongting, Yang, Guo-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201919/
https://www.ncbi.nlm.nih.gov/pubmed/25315906
http://dx.doi.org/10.1186/s12974-014-0177-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201919/
https://www.ncbi.nlm.nih.gov/pubmed/25315906
http://dx.doi.org/10.1186/s12974-014-0177-4

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