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Systems level mapping of metabolic complexity in Mycobacterium tuberculosis to identify high-value drug targets
BACKGROUND: The effectiveness of current therapeutic regimens for Mycobacterium tuberculosis (Mtb) is diminished by the need for prolonged therapy and the rise of drug resistant/tolerant strains. This global health threat, despite decades of basic research and a wealth of legacy knowledge, is due to...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201925/ https://www.ncbi.nlm.nih.gov/pubmed/25304862 http://dx.doi.org/10.1186/s12967-014-0263-5 |