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Systems level mapping of metabolic complexity in Mycobacterium tuberculosis to identify high-value drug targets

BACKGROUND: The effectiveness of current therapeutic regimens for Mycobacterium tuberculosis (Mtb) is diminished by the need for prolonged therapy and the rise of drug resistant/tolerant strains. This global health threat, despite decades of basic research and a wealth of legacy knowledge, is due to...

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Detalles Bibliográficos
Autores principales:	Vashisht, Rohit, Bhat, Ashwini G, Kushwaha, Shreeram, Bhardwaj, Anshu, Consortium, OSDD, Brahmachari, Samir K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201925/ https://www.ncbi.nlm.nih.gov/pubmed/25304862 http://dx.doi.org/10.1186/s12967-014-0263-5

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