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Interaction between HIV-1 Tat and DNA-PKcs modulates HIV transcription and class switch recombination

HIV-1 tat targets a variety of host cell proteins to facilitate viral transcription and disrupts host cellular immunity by inducing lymphocyte apoptosis, but whether it influences humoral immunity remains unclear. Previously, our group demonstrated that tat depresses expression of DNA-PKcs, a critic...

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Detalles Bibliográficos
Autores principales: Zhang, Shi-Meng, Zhang, He, Yang, Tian-Yi, Ying, Tian-Yi, Yang, Pei-Xiang, Liu, Xiao-Dan, Tang, Sheng-Jian, Zhou, Ping-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202030/
https://www.ncbi.nlm.nih.gov/pubmed/25332688
http://dx.doi.org/10.7150/ijbs.10366