Cargando…

Interaction between HIV-1 Tat and DNA-PKcs modulates HIV transcription and class switch recombination

HIV-1 tat targets a variety of host cell proteins to facilitate viral transcription and disrupts host cellular immunity by inducing lymphocyte apoptosis, but whether it influences humoral immunity remains unclear. Previously, our group demonstrated that tat depresses expression of DNA-PKcs, a critic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Shi-Meng, Zhang, He, Yang, Tian-Yi, Ying, Tian-Yi, Yang, Pei-Xiang, Liu, Xiao-Dan, Tang, Sheng-Jian, Zhou, Ping-Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202030/ https://www.ncbi.nlm.nih.gov/pubmed/25332688 http://dx.doi.org/10.7150/ijbs.10366

Ejemplares similares

DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination
por: Franco, Sonia, et al.
Publicado: (2008)

HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription
por: Ivanov, Andrey, et al.
Publicado: (2018)

Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription
por: Ammosova, Tatyana, et al.
Publicado: (2006)

Quantitative Regulation of Class Switch Recombination by Switch Region Transcription
por: Lee, Chung-Gi, et al.
Publicado: (2001)

Dynamic interactions of the HIV-1 Tat with nucleic acids are critical for Tat activity in reverse transcription
por: Boudier, Christian, et al.
Publicado: (2014)

Tat IRES modulator of tat mRNA (TIM-TAM): a conserved RNA structure that controls Tat expression and acts as a switch for HIV productive and latent infection
por: Khoury, Georges, et al.
Publicado: (2020)

SIRT1 Regulates HIV Transcription via Tat Deacetylation
por: Pagans, Sara, et al.
Publicado: (2005)

9-aminoacridine Inhibition of HIV-1 Tat Dependent Transcription
por: Guendel, Irene, et al.
Publicado: (2009)

Identification of HIV-1 Tat-Associated Proteins Contributing to HIV-1 Transcription and Latency
por: Jean, Maxime Junior, et al.
Publicado: (2017)

Processing of Switch Transcripts Is Required for Targeting of Antibody Class Switch Recombination
por: Hein, Katharina, et al.
Publicado: (1998)

UHRF1 Suppresses HIV-1 Transcription and Promotes HIV-1 Latency by Competing with p-TEFb for Ubiquitination-Proteasomal Degradation of Tat
por: Liang, Taizhen, et al.
Publicado: (2021)

Strategies to Block HIV Transcription: Focus on Small Molecule Tat Inhibitors
por: Mousseau, Guillaume, et al.
Publicado: (2012)

Modulation of microtubule assembly by the HIV-1 Tat protein is strongly dependent on zinc binding to Tat
por: Egelé, Caroline, et al.
Publicado: (2008)

HIV-1 Tat and T cell apoptosis
por: Krammer, Peter H
Publicado: (2006)

60404 HIV Tat Induced Neuroinflammation
por: Carey, Sean, et al.
Publicado: (2021)

HIV-Tat protein-accelerated aging
por: Kaufman, Marc J., et al.
Publicado: (2022)

Astrocytic metabolic switch is a novel etiology for Cocaine and HIV-1 Tat-mediated neurotoxicity
por: Natarajaseenivasan, Kalimuthusamy, et al.
Publicado: (2018)

The role of HIV Tat protein in HIV-related cardiovascular diseases
por: Jiang, Yanan, et al.
Publicado: (2018)

Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR
por: Van Duyne, Rachel, et al.
Publicado: (2008)

Phosphorylation of HIV Tat by PKR increases interaction with TAR RNA and enhances transcription
por: Endo-Munoz, Liliana, et al.
Publicado: (2005)

A New Paradigm in Eukaryotic Biology: HIV Tat and the Control of Transcriptional Elongation
por: Barboric, Matjaz, et al.
Publicado: (2005)

Controlling Cellular P-TEFb Activity by the HIV-1 Transcriptional Transactivator Tat
por: Muniz, Lisa, et al.
Publicado: (2010)

Shutdown of HIV-1 Transcription in T Cells by Nullbasic, a Mutant Tat Protein
por: Jin, Hongping, et al.
Publicado: (2016)

DDX5 potentiates HIV-1 transcription as a co-factor of Tat
por: Sithole, Nyaradzai, et al.
Publicado: (2020)

Mechanism of HIV-1 Tat RNA translation and its activation by the Tat protein
por: Charnay, Nicolas, et al.
Publicado: (2009)

Overexpression of recombinant HIV-1 Subtype C Tat and Nef in a Salmonella vaccine vector
por: Chin’ombe, Nyasha, et al.
Publicado: (2013)

Immune regulator ABIN1 suppresses HIV-1 transcription by negatively regulating the ubiquitination of Tat
por: Chen, Shiyou, et al.
Publicado: (2017)

Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription
por: Barboric, Matjaz, et al.
Publicado: (2007)

AIDing Chromatin and Transcription-Coupled Orchestration of Immunoglobulin Class-Switch Recombination
por: Vaidyanathan, Bharat, et al.
Publicado: (2014)

Long-Range Control of Class Switch Recombination by Transcriptional Regulatory Elements
por: Dauba, Audrey, et al.
Publicado: (2021)

Characterization of Tat Antibody Responses in Chinese Individuals Infected with HIV-1
por: Chen, Qiuli, et al.
Publicado: (2013)

PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription
por: Faust, Tyler B., et al.
Publicado: (2017)

NUCKS1, a novel Tat coactivator, plays a crucial role in HIV-1 replication by increasing Tat-mediated viral transcription on the HIV-1 LTR promoter
por: Kim, Hye-Young, et al.
Publicado: (2014)

Proteomic characterization of HIV-1 Tat interactome
por: Gautier, VW, et al.
Publicado: (2006)

HIV-1 Tat: Role in Bystander Toxicity
por: Ajasin, David, et al.
Publicado: (2020)

Substrate-triggered position switching of TatA and TatB during Tat transport in Escherichia coli
por: Habersetzer, Johann, et al.
Publicado: (2017)

Cellular RelB interacts with the transactivator Tat and enhance HIV-1 expression
por: Wang, Meng, et al.
Publicado: (2018)

Effect of SWI/SNF chromatin remodeling complex on HIV-1 Tat activated transcription
por: Agbottah, Emmanuel, et al.
Publicado: (2006)

Accurate Prediction of Transcriptional Activity of Single Missense Variants in HIV Tat with Deep Learning
por: Derbel, Houssemeddine, et al.
Publicado: (2023)

KU-0060648 inhibits hepatocellular carcinoma cells through DNA-PKcs-dependent and DNA-PKcs-independent mechanisms
por: Chen, Min-Bin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_vv34gjqj7526s6ap974iv2ps2c