Kinetic analysis of antagonist-occupied adenosine-A(3) receptors within membrane microdomains of individual cells provides evidence of receptor dimerization and allosterism

In our previous work, using a fluorescent adenosine-A(3) receptor (A(3)AR) agonist and fluorescence correlation spectroscopy (FCS), we demonstrated high-affinity labeling of the active receptor (R*) conformation. In the current study, we used a fluorescent A(3)AR antagonist (CA200645) to study the b...

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Detalles Bibliográficos
Autores principales: Corriden, Ross, Kilpatrick, Laura E., Kellam, Barrie, Briddon, Stephen J., Hill, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2014
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202110/
https://www.ncbi.nlm.nih.gov/pubmed/24970394
http://dx.doi.org/10.1096/fj.13-247270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202110/
https://www.ncbi.nlm.nih.gov/pubmed/24970394
http://dx.doi.org/10.1096/fj.13-247270

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