Acetylation-defective mutants of Pparγ are associated with decreased lipid synthesis in breast cancer cells

In our prior publications we characterized a conserved acetylation motif (K(R)xxKK) of evolutionarily related nuclear receptors. Recent reports showed that peroxisome proliferator activated receptor gamma (PPARγ) deacetylation by SIRT1 is involved in delaying cellular senescence and maintaining the...

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Detalles Bibliográficos
Autores principales: Tian, Lifeng, Wang, Chenguang, Hagen, Fred K., Gormley, Michael, Addya, Sankar, Soccio, Raymond, Casimiro, Mathew C., Zhou, Jie, Powell, Michael J., Xu, Ping, Deng, Haiteng, Sauve, Anthony A., Pestell, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202124/
https://www.ncbi.nlm.nih.gov/pubmed/25229978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202124/
https://www.ncbi.nlm.nih.gov/pubmed/25229978

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