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TRIM8 anti-proliferative action against chemo-resistant renal cell carcinoma

In some tumours, despite a wild-type p53 gene, the p53 pathway is inactivated by alterations in its regulators or by unknown mechanisms, leading to resistance to cytotoxic therapies. Understanding the mechanisms of functional inactivation of wild-type p53 in these tumours may help to define prospect...

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Detalles Bibliográficos
Autores principales: Caratozzolo, Mariano Francesco, Valletti, Alessio, Gigante, Margherita, Aiello, Italia, Mastropasqua, Francesca, Marzano, Flaviana, Ditonno, Pasquale, Carrieri, Giuseppe, Simonnet, Hélène, D'Erchia, Anna Maria, Ranieri, Elena, Pesole, Graziano, Sbisà, Elisabetta, Tullo, Apollonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202135/
https://www.ncbi.nlm.nih.gov/pubmed/25277184