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High mobility group Box-1 inhibits cancer cell motility and metastasis by suppressing activation of transcription factor CREB and nWASP expression

The ability to metastasize is a hallmark of malignant tumors, and metastasis is the principal cause of death of cancer patients. The High Mobility Group Box-1 (HMGB1) is a multifunction protein that serves as both a chromatin protein and an extracellular signaling molecule. Our current study demonst...

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Detalles Bibliográficos
Autores principales: Zuo, Zhenghong, Che, Xun, Wang, Yulei, Li, Bowen, Li, Jingxia, Dai, Wei, Lin, Charles P., Huang, Chuanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202136/
https://www.ncbi.nlm.nih.gov/pubmed/25277185