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Aurora kinase A suppresses metabolic stress-induced autophagic cell death by activating mTOR signaling in breast cancer cells

Aberrant Aur-A signaling is associated with tumor malignant behaviors. However, its involvement in tumor metabolic stress is not fully elucidated. In the present study, prolonged nutrient deprivation was conducted into breast cancer cells to mimic metabolic stress in tumors. In these cells, autophag...

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Detalles Bibliográficos
Autores principales: Xu, Ling-Zhi, Long, Zi-Jie, Peng, Fei, Liu, Yang, Xu, Jie, Wang, Chang, Jiang, Lei, Guo, Tao, Kamran, Muhammad, Li, Si-Si, Wang, Chun-Li, Wang, Hong-Jiang, Zhao, Yong-Fu, Wan, Xian-Yao, Liu, Quentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202139/
https://www.ncbi.nlm.nih.gov/pubmed/25115395