Cargando…

Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells

p53 transduction is a potentially effective cancer therapy but does not result in a good therapeutic response in all human cancers due to resistance to apoptosis. To discover factors that overcome resistance to p53-induced apoptosis, we attempted to identify RNAi sequences that enhance p53-induced a...

Descripción completa

Detalles Bibliográficos
Autores principales: Idogawa, Masashi, Ohashi, Tomoko, Sugisaka, Jun, Sasaki, Yasushi, Suzuki, Hiromu, Tokino, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202142/
https://www.ncbi.nlm.nih.gov/pubmed/25277188