βTrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy

In mammals, cell cycle progression is controlled by cyclin-dependent kinases, among which CDK1 plays important roles in the regulation of the G2/M transition, G1 progression and G1/S transition. CDK1 is highly regulated by its association to cyclins, phosphorylation and dephosphorylation, changes in...

Descripción completa

Detalles Bibliográficos
Autores principales: Herrero-Ruiz, Joaquín, Mora-Santos, Mar, Giráldez, Servando, Sáez, Carmen, Japón, Miguel Á., Tortolero, Maria, Romero, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202144/
https://www.ncbi.nlm.nih.gov/pubmed/25149538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202144/
https://www.ncbi.nlm.nih.gov/pubmed/25149538

Ejemplares similares