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CLDN3 inhibits cancer aggressiveness via Wnt-EMT signaling and is a potential prognostic biomarker for hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most common fatal malignancies but the molecular genetic basis of this disease remains unclear. By using genome-wide methylation profiling analysis, we identified CLDN3 as an epigenetically regulated gene in cancer. Here, we investigated its function and...

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Detalles Bibliográficos
Autores principales: Jiang, Lei, Yang, Yi-Dong, Fu, Li, Xu, Weiqi, Liu, Dabin, Liang, Qiaoyi, Zhang, Xiang, Xu, Lixia, Guan, Xin-Yuan, Wu, Bin, Sung, Joseph J.Y., Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202152/
https://www.ncbi.nlm.nih.gov/pubmed/25277196