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Amphipathic tail-anchoring peptide is a promising therapeutic agent for prostate cancer treatment

Amphipathic tail-anchoring peptide (ATAP) derived from the human anti-apoptotic protein Bfl-1 is a potent inducer of apoptosis by targeting mitochondria permeability transition. By linking ATAP to an internalizing RGD peptide (iRGD), selective targeting for ATAP to tumor cell was achieved. Confocal...

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Detalles Bibliográficos
Autores principales: De, Gejing, Ko, Jae-Kyun, Tan, Tao, Zhu, Hua, Li, Haichang, Ma, Jianjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202157/
https://www.ncbi.nlm.nih.gov/pubmed/25245280