Fucoidan inhibition of lung cancer in vivo and in vitro: role of the Smurf2-dependent ubiquitin proteasome pathway in TGFβ receptor degradation

Fucoidan, a polysaccharide extracted from brown seaweeds, reduces tumor cell proliferation. In this study, we demonstrate that fucoidan reduces tumor size in LLC1-xenograft male C57BL/6 mice. Moreover, we found that LLC1-bearing mice continuously fed fucoidan showed greater antitumor activity than m...

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Detalles Bibliográficos
Autores principales: Hsu, Hsien-Yeh, Lin, Tung-Yi, Wu, Yu-Chung, Tsao, Shu-Ming, Hwang, Pai-An, Shih, Yu-Wei, Hsu, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202167/
https://www.ncbi.nlm.nih.gov/pubmed/25149540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202167/
https://www.ncbi.nlm.nih.gov/pubmed/25149540

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