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Mutant NRAS(Q61) shares signaling similarities across various cancer types – potential implications for future therapies

Oncogenic mutations in the Neuroblastoma Rat Sarcoma oncogene (NRAS) are frequent in melanoma, but are also found in several other cancer types, such as lung cancer, neuroblastoma and colon cancer. We designed our study to analyze changes in NRAS mutant tumor cells derived from malignancies other th...

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Detalles Bibliográficos
Autores principales: Vujic, Igor, Posch, Christian, Sanlorenzo, Martina, Yen, Adam J., Tsumura, Aaron, Kwong, Andrew, Feichtenschlager, Valentin, Lai, Kevin, Arneson, Douglas V., Rappersberger, Klemens, Ortiz-Urda, Susana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202171/
https://www.ncbi.nlm.nih.gov/pubmed/25277205