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Reconstruction of metabolic pathways by combining probabilistic graphical model-based and knowledge-based methods

Automatic reconstruction of metabolic pathways for an organism from genomics and transcriptomics data has been a challenging and important problem in bioinformatics. Traditionally, known reference pathways can be mapped into an organism-specific ones based on its genome annotation and protein homolo...

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Detalles Bibliográficos
Autores principales: Qi, Qi, Li, Jilong, Cheng, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202177/
https://www.ncbi.nlm.nih.gov/pubmed/25374614
http://dx.doi.org/10.1186/1753-6561-8-S6-S5