Autophagy inhibition sensitizes hepatocellular carcinoma to the multikinase inhibitor linifanib

Autophagy is a critical survival pathway for cancer cells under conditions of stress. Thus, induction of autophagy has emerged as a drug resistance mechanism. This study is to determine whether autophagy is activated by a novel multikinase inhibitor linifanib, thereby impairing the sensitivity of he...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Hongming, Wang, Zhanggui, Jiang, Liming, Sui, Xinbing, You, Liangkun, Shou, Jiawei, Jing, Zhao, Xie, Jiansheng, Ge, Weiting, Cai, Xiujun, Huang, Wendong, Han, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202209/
https://www.ncbi.nlm.nih.gov/pubmed/25327881
http://dx.doi.org/10.1038/srep06683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202209/
https://www.ncbi.nlm.nih.gov/pubmed/25327881
http://dx.doi.org/10.1038/srep06683

Ejemplares similares