Methylation of histone H4 at aspartate 24 by Protein L-isoaspartate O-methyltransferase (PCMT1) links histone modifications with protein homeostasis

Histone modifications play crucial roles in modulating chromatin function and transcriptional activity. Due to their long half-life, histones can, in addition to post-translational modifications, also accumulate spontaneous chemical alterations, which can affect their functionality and require eithe...

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Detalles Bibliográficos
Autores principales: Biterge, Burcu, Richter, Florian, Mittler, Gerhard, Schneider, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202215/
https://www.ncbi.nlm.nih.gov/pubmed/25327473
http://dx.doi.org/10.1038/srep06674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202215/
https://www.ncbi.nlm.nih.gov/pubmed/25327473
http://dx.doi.org/10.1038/srep06674

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