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Analysis of purified Wild type and mutant adenovirus particles by SILAC based quantitative proteomics

We used SILAC (stable isotope labelling of amino acids in cell culture) and high-throughput quantitative MS mass spectrometry to analyse the protein composition of highly purified WT wild type adenoviruses, mutant adenoviruses lacking an internal protein component (protein V) and recombinant adenovi...

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Detalles Bibliográficos
Autores principales: Alqahtani, Ali, Heesom, Kate, Bramson, Jonathan L., Curiel, David, Ugai, Hideyo, Matthews, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202269/
https://www.ncbi.nlm.nih.gov/pubmed/25096814
http://dx.doi.org/10.1099/vir.0.068221-0