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A hybrid clustering approach to recognition of protein families in 114 microbial genomes

BACKGROUND: Grouping proteins into sequence-based clusters is a fundamental step in many bioinformatic analyses (e.g., homology-based prediction of structure or function). Standard clustering methods such as single-linkage clustering capture a history of cluster topologies as a function of threshold...

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Detalles Bibliográficos
Autores principales: Harlow, Timothy J, Gogarten, J Peter, Ragan, Mark A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420232/
https://www.ncbi.nlm.nih.gov/pubmed/15115543
http://dx.doi.org/10.1186/1471-2105-5-45