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Diversity and repertoire of IgW and IgM VH families in the newborn nurse shark

BACKGROUND: Adult cartilaginous fish express three immunoglobulin (Ig) isotypes, IgM, IgNAR and IgW. Newborn nurse sharks, Ginglymostoma cirratum, produce 19S (multimeric) IgM and monomeric/dimeric IgM(1gj), a germline-joined, IgM-related VH, and very low amounts of 7S (monomeric) IgM and IgNAR prot...

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Detalles Bibliográficos
Autores principales: Rumfelt, Lynn L, Lohr, Rebecca L, Dooley, Helen, Flajnik, Martin F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420240/
https://www.ncbi.nlm.nih.gov/pubmed/15132758
http://dx.doi.org/10.1186/1471-2172-5-8