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Scambio, a novel guanine nucleotide exchange factor for Rho

BACKGROUND: Small GTPases of the Rho family are critical regulators of various cellular functions including actin cytoskeleton organization, activation of kinase cascades and mitogenesis. For this reason, a major objective has been to understand the mechanisms of Rho GTPase regulation. Here, we exam...

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Detalles Bibliográficos
Autores principales: Curtis, Christina, Hemmeryckx, Bianca, Haataja, Leena, Senadheera, Dinithi, Groffen, John, Heisterkamp, Nora
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420252/
https://www.ncbi.nlm.nih.gov/pubmed/15107133
http://dx.doi.org/10.1186/1476-4598-3-10